Neurodegenerative Disorders and Why Cannabinoids Can Help the Current Poor Therapeutic Outcomes
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We know that medical interventions for neurodegenerative diseases (Alzheimer’s, Multiple Sclerosis, Parkinson’s, ALS, etc…) don’t have the best of success rates. Many times, medications do little more than keep patients comfortable and few, if any, can do anything to reverse the conditions.

I’m not here to tell you that CBD is going to directly cure neurodegenerative diseases but I will tell you that research is beginning to show that CBD can do a lot to help people with such conditions, and its results go far beyond just ‘keeping patients comfortable.’  ‘The Decade of the Brain’, the 1990s as declared by Congress, left much to be desired.   Even with a large amount of money going into medical research to address these diseases, results are simply not where they should be. Perhaps they’re partly looking in the wrong places?  Perhaps they’re addressing the conditions too late?  We all know prevention is the best medicine and sometimes conditions can be so bad that there simply is no way to fix what is broken.  This is why a healthy lifestyle is so important.

To best ward off the likelihood of future neurological damage (and other body and health issues), it makes sense to reduce the stress on the brain and body starting at an early age.  From the doctor and fitness professional side of me, I always recommend keeping healthy body composition numbers, staying active (be sure to work on mobility and dynamic stability), keeping the antioxidants flowing, optimizing neurological function, and doing all you can to minimize the effects of stress.  This is one main reason as to why I’m so into the CBD.  ‘We all have stress…and stress doesn’t kill us…it’s how we deal with stress that ultimately determines our fate!’  Your endocannabinoid system  (ECS or eCB) helps you to better cope with stress.  Being most peoples’ ECS is dysfunctional, it only makes sense to help ensure our ECS operates as it should!  Enter CBD…

Specifically regarding the topic of this blog, if one looks up the effects of CBD on Alzheimer’s Disease, there is plenty of information to be found.  One such study that contains a lot of good information is by Tim Karl et al. in Behavioural Pharmacology, 2017.  There are many more on similar subject material. 

The most exciting study to cover on this topic is by Javier Fernandez-Ruiz (June 2018) and it is titled ‘The Biomedical Challenge of Neurodegenerative Disorders: an Opportunity for Cannabinoid-based Therapies to Improve on the Poor Current Therapeutic Outcomes.‘  This article is meant to shed light on the power cannabinoids can have with helping those with neurodegenerative diseases.

The author believes that cannabinoids can act on their own or with a combination of certain medications to help with neuroprotective effects. Cannabinoids act to ‘reduce excitotoxicity, oxidative stress, glial activation, and can work to promote autophagy (eating away at unhealthy cells), eliminate protein aggregates (incorrectly folded and dangerous proteins), and enhance metabolic and neurotrophic support.’  Not only can cannabinoids activate NPC proliferation but they can also help with cell replacement and this is important for those with neurodegenerative diseases that have set in for a while.  Of course, it’s best to reverse the condition as opposed to just ‘treat’ it.  CBD appears to help with both.

CBD exerts neuroprotective and neuroreparative effects by enhancing the ECS as the ECS itself acts as a neurological modulating system and also because the ECS is directly located in the Central Nervous System and in structures associated with neurodegenerative diseases.  It also has an influence on ‘preservation, rescue, repair and replacement of neurons’.  The author concludes by discussing how 15 years of research on cannabinoid-based therapies has provided ‘solid evidence’ to justify further investigation.

At Noetic, we believe it is a great idea to supplement CBD alone or in conjunction with medications someone with a neurodegenerative disease might already be taking.  Of course, we’d love to see the person not need as much or any of the medications (after all, they tend to have potentially serious side effects).  As was discussed in the study, current medications are not getting the job done.  Why not try something that is natural, likely yields amazing results, and is safe? Consult with your medical doctor and show them this blog and studies, if necessary.

CBD can likely dramatically improve your quality of life if you have a neurodegenerative disease. It’s certainly worth a try!  We recommend our new CBD Nasal Spray as this is the most direct way to get CBD into your brain (it crosses the blood-brain-barrier).  Another option is one of our tinctures at they will help augment or establish a properly functioning Endocannabinoid System to help with a plethora of health issues.

Enjoy the NN lifestyle!

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